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KMID : 1146920210510010023
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Journal of Pharmaceutical Investigation
2021 Volume.51 No. 1 p.23 ~ p.34
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Bacteriophages: cancer diagnosis, treatment, and future prospects
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Abbaszadeh Faezeh
Leylabadlo Hamed Ebrahimzadeh
Alinezhad Farbod
Feizi Hadi
Mobed Ahmad
Baghbanijavid Shabnam
Baghi Hossein Bannazadeh
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Abstract
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Background: Early diagnosis is one of the most important factors in cancer treatment. Unfortunately, despite remarkable advances in the diagnosis and treatment methods of cancers in recent years, these methods are far from being perfect and have significant limitations and disadvantages. High costs and unwanted damage to healthy cells are some of the most important challenges.
Area covered: With the advent of novel technologies, potentially advantageous methods are being studied actively. The use of bacteriophages is one of the modern methods for cancer diagnosis and treatment. In the present article, we will discuss the potential advantages and limitations regarding the use of bacteriophages in the diagnosis and treatment of malignancies.
Expert opinion: The use of bacteriophages is one of the more recent methods for cancer diagnosis and treatment. Due to the non-pathogenic nature of bacteriophages, their genetic engineering capability makes them a great option for therapeutic purposes. The exact potential of phages to be used in the diagnosis and treatment of cancer, will be determined with further research in the future.
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KEYWORD
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Bacteriophages, Cancer diagnosis, Cancer immunotherapy, Phage therapy
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